CaPS

Webserver for prediction of EF-hand or EF-hand like Ca2+-binding motifs

https://shenghuixue.github.io/CAPS/index.html

EF-hand CaBPs data library

Database of sequence and structural information on EF-hand CaBPs

http://structbio.vanderbilt.edu/cabp_database/cabp.html

EF-Handome

A collection of gene, mRNA and protein information of EF-hand proteins in human, rat and mouse

Available from the authors

MFSCa

A meta-functional signature algorithm for Ca2+-binding residue prediction

Available from the authors

MetalloPred

Webserver for prediction of metal-binding sites using cascade of neural networks from sequence derived features

http://www.juit.ac.in/attachments/Metallopred/prediction.html

CalPred

Web tools for EF-hand CaBP prediction and calcium binding region identification

http://www.bioinformatics.org/calpred/index.html

Predicting Ca2+-binding sites based on protein structures (PDB entries or modeled structures)

MUGπ

Tools for predicting Ca2+-binding sites based on graph theory and geometric analyses

https://calciomics.org/

Fold-X

A computations algorithm based on empirical force field to predict the position of metal ions in protein

http://foldx.crg.es/

SVMProt

Webserver for assigning protein functions (including Ca2+-binding) with support vector machine learning

http://bidd2.nus.edu.sg/cgi-bin/svmprot/svmprot.cgi

WebFEATURE

Webserver for automated function prediction (including Ca2+-binding sites) in protein structures with machine learning

 

SitePredict

Webserver for predicting metal ion binding sites with the Random Forest machine learning method

 

FunFOLD

An integrated web resource for ligand binding site prediction

http://www.reading.ac.uk/bioinf/FunFOLD/FunFOLD_form.html

FINDSITE-metal

A threading-based method to detect metal-binding site in modeled structures by integrating evolutionary information and machine learning

 

MetaPocket

A consensus method to predict ligand binding sites by integrating LIGSITE, PASS, Q-SiteFinder and SURFNET, Fpocket, GHECOM, ConCavity and POCASA

 

MetSite

An automatic approach for detecting metal-binding residues in low-resolution 3D models by with neural network classifiers

 

Predicting Ca2+-modulated functions

Calmodulin Target Database

Webserver for predicting calmodulin binding sites from protein sequences

http://calcium.uhnres.utoronto.ca/ctdb/ctdb/home.html

MeTaDor

Webserver for predicting membrane targeting domains (e.g., Ca2+-dependent C2 domain)

 

ORBIT

De novo design of protein sequence based on a desired backbone fold

Available from the authors

DEZYMER

Design of metal binding sties by selecting suitable ligands

Available from the authors